background

Premature infants often develop into neuromotor and cognitive developmental disorders. The best way to reduce the impact of these disorders is to get the most out of the situation through a series of cognitive and exercise tests. However, accurately measuring and recording the child's motor function is a complex task. As every parent will tell you, toddlers don't like to wear bulky equipment on their hands and prefer to eat things they shouldn't eat.

Wearable devices have become an important innovation in disease diagnosis and treatment, and play an extremely important role in human physiological indicators and functional monitoring. Previously, the author introduced many related scientific research cases, and I will not list them here. Today, let's take a look at how wearable devices can help measure children's motor function.

Innovation

Recently, researchers at Harvard University in the United States have developed a soft, non-toxic wearable sensor that can be worn invisibly on the hand, measuring the strength of the grip and the movement of the hands and fingers.

The study, published in the journal Advanced Functional Materials, is the Harvard University's John Paulson School of Engineering and Applied Science (SEAS), the Wyss Bioinspired Engineering Institute, the Beth Israel Deaconess Medical Center, and Boston. The results of cooperative development of children's hospitals.

The Harvard University Technology Development Office has proposed a portfolio of intellectual property related to the new flexible sensor architecture and is seeking commercial opportunities for these technologies.

technology

A new element of this sensor is a non-toxic, highly conductive solution. “We have developed a new type of conductive liquid that is comparable to a small drop of salt water. It is more conductive than previous biocompatible liquids and will lead to cleaner,” said SEAS graduate student and first author of the paper, Siyi Xu. , the goal of less noisy data."

This sensory solution consists of potassium iodide and glycerin. Potassium iodide oral solution is a dietary supplement. Glycerin is a common food additive. After mixing for a short period of time, glycerol breaks the crystal structure of potassium iodide and forms potassium ions (K+) and iodide ions (I-), making the liquid conductive. Since glycerol has a lower evaporation rate than water and potassium iodide is highly soluble, the solution not only maintains stability over a range of temperatures and humidities, but also has high electrical conductivity.

Xu said: “Before, the biocompatible flexible sensor consisted of a chloride-glycerin solution, but the conductivity of these solutions was poor, making the noise of the sensor data very large and took 10 hours to prepare. This time has been reduced to 20 minutes and very clean data has been obtained."

The sensor is also designed to take into account the needs of children. Unlike bulky gloves, this silicone rubber sensor is placed over the finger and on the fingertip.

One of the co-authors, Eugene Goldfield, associate professor of behavioral science at Boston Children's Hospital and Harvard Medical School, and associate professor of Harvard University's Wyss Institute, is the lead researcher at the Wyss Institute's Research Children's Flexible Electronics Program, which is premature and has cerebral palsy. Children have designed a modular robotic system.

Goldfield and colleagues are currently using SEAS and Wyss' motion capture labs to study motor function. Although motion capture can tell us a lot about exercise, it can't measure strength, and strength is critical for diagnosing neuromotor and cognitive developmental disorders.

value

Eugene Goldfield, an associate professor of behavioral science at Boston Children's Hospital and Harvard Medical School and an associate professor at Harvard Medical School's Wyss Institute, said: "We often see children with premature birth or early diagnosis of early developmental disorders with highly sensitive skin. By attaching this device to your finger, you can get accurate information and take into account the sensitivity of your child's hand."

Goldfield said: "Early diagnosis is important for treating these developmental disorders. This wearable sensor gives us the advantages we don't currently have."

Rob Wood, a professor of engineering and applied science at SEAS and a founding core faculty member at the Wyss Institute, said: "The ability to quantify complex human movements has brought us an unprecedented diagnostic tool. Focus on the development of children's motor skills, How to integrate many sensors into a small, lightweight, unobtrusive wearable device presents unique challenges. These new sensors solve these challenges, and if we can create wearable sensors that are so capable of such a daunting task, We believe it will also open applications in diagnostics, therapy, human-computer interaction interfaces and virtual reality."

future

This paper only tested the device in adult hands. Next, the researchers plan to shrink the device and test it in the hands of children.

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